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NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges Seems to play an essential

SKU: 40587178985

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SEK162.00 SEK189.00

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NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges Seems to play an essentialNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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Description

Seems to play an essential role in cold-induced suppression of cell proliferation

The protein binds to collagen IV and laminin

Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth

Mutations in this gene have been associated with geroderma osteodysplastica

depending on stage of neuronal maturation and neuron type

NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges Seems to play an essentialNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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