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PCNA Monoclonal Antibody(12D10), 50ul Variant Libraries The protein encoded by this

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PCNA Monoclonal Antibody(12D10), 50ul Variant Libraries The protein encoded by thisThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have

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Description

The protein encoded by this gene is a member of the immunophilin protein family

The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein family

It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation| DNA repair| and/or cell cycle checkpoint control

designated the Sec insertion sequence (SECIS) element

PCNA Monoclonal Antibody(12D10), 50ul Variant Libraries The protein encoded by thisThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have

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