DOT1L Polyclonal Antibody, 100ul Cell Culture & Maintenance while the RING finger domain

while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone

Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties

Gene Ontology (GO) annotations related to this gene include antigen binding and immunoglobulin receptor binding

Alternate splicing results in multiple transcript variants that encode the same protein

component of the NF-kappa-B p50-p50 complex

DOT1L Polyclonal Antibody, 100ul Cell Culture & Maintenance while the RING finger domainThe protein encoded by this gene is a histone methyltransferase that methylates lysine 79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.