DFNA5 Polyclonal Antibody, 100ul Drug Development and Evaluation VRK3 (vaccinia related kinase 3)

VRK3 (vaccinia related kinase 3) encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases

ALK/KIF5B (chromosome 10)

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family

Cytochrome P450 2C8/9/18/19 localizes to the endoplasmic reticulum but its specific substrate has not yet been determined

Two pseudogenes of this gene have been identified on chromosomes 10 and 4

DFNA5 Polyclonal Antibody, 100ul Drug Development and Evaluation VRK3 (vaccinia related kinase 3)Hearing impairment is a heterogeneous condition with over 40 loci described. Non syndromic hearing impairment protein 5 encoded by DFNA5 is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.