SC65 Polyclonal Antibody, 100ul Recombinant Ab Production Transcription factor required for TBX21/T-bet-dependent

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression

The encoded protein is known to play a role in cystic fibrosis and Huntington's disease

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho

Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site

Several alternatively spliced transcript variants have been observed

SC65 Polyclonal Antibody, 100ul Recombinant Ab Production Transcription factor required for TBX21/T-bet-dependentThis nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.