Siah-2 Polyclonal Antibody, 50ul Measuring Instruments This gene is an oncogene

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR)

subunit:Interacts with FRAP1

This domain exists as a homodimer

This gene was identified as an oncogene

Siah-2 Polyclonal Antibody, 50ul Measuring Instruments This gene is an oncogeneSIAH2 encodes E3 ubiquitin protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.