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APS Polyclonal Antibody, 100ul Recombinant Protein Expression This gene encodes a member

SKU: 39726686330

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PLN141.00 PLN177.00

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APS Polyclonal Antibody, 100ul Recombinant Protein Expression This gene encodes a memberThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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Description

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin

RNA transport

The protein encoded by EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3) phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2

Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival

May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage

APS Polyclonal Antibody, 100ul Recombinant Protein Expression This gene encodes a memberThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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