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GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Mutations in this gene have

SKU: 39633546110

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PLN141.00 PLN176.00

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GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Mutations in this gene haveNR3C1 encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and

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Description

Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14

Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis

Protein kinase C delta by PRKCD is one of the PKC family members

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus

including ankyrin-like repeats

GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Mutations in this gene haveNR3C1 encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and

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