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CUL-1 Polyclonal Antibody, 50ul[BT-AP08190] Adeno-associated Virus Packaging AChRα10 forms a hetero-oligomeric channels

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CUL-1 Polyclonal Antibody, 50ul[BT-AP08190] Adeno-associated Virus Packaging AChRα10 forms a hetero-oligomeric channelsCore component of multiple cullin RING based SCF (SKP1 CUL1 F box protein) E3 ubiquitin protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1 F box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin conjugating enzyme. The E3

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Description

AChRα10 forms a hetero-oligomeric channels in conjunction with AChRα9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli

Among its related pathways areTranscription factor regulation in adipogenesisand Folate-Alcohol and Cancer Pathway

CCL14 (chemokine (C-C motif) ligand 14)

This gene encodes a mitochondrial acetyl-CoA synthetase enzyme

Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5

CUL-1 Polyclonal Antibody, 50ul[BT-AP08190] Adeno-associated Virus Packaging AChRα10 forms a hetero-oligomeric channelsCore component of multiple cullin RING based SCF (SKP1 CUL1 F box protein) E3 ubiquitin protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1 F box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin conjugating enzyme. The E3

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