Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables consisting of an extracellular region

consisting of an extracellular region

Preferentially binds the chromophore 11-cis retinal and is a bistable protein that displays emission peaks at 380 nm (UVA light) and 470 nm (blue light) (PubMed: 22043319)

An important paralog of this gene is ZNF229

The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled| a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin

There are several related pseudogenes on chromosome 7

Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables consisting of an extracellular regionABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11452359, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed: 11099417, PubMed: 11452359, PubMed: