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GCH1 Polyclonal Antibody, 20ul Enzyme Activity Assays whereas the other four melanocortin

SKU: 39271214250

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GCH1 Polyclonal Antibody, 20ul Enzyme Activity Assays whereas the other four melanocortinThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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Description

whereas the other four melanocortin receptors recognize a variety of melanocortin ligands

Among its related pathways are LKB1 signaling events

and mediate the signal transduction from various receptors of the TNFR superfamily

The encoded isozyme is a soluble cytoplasmic protein

PAX5 is located at 9p13

GCH1 Polyclonal Antibody, 20ul Enzyme Activity Assays whereas the other four melanocortinThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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