KR103 Rabbit Polyclonal Antibody, 50ul Organelle Studies Mutations in this gene cause

Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6

The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon

The TRIM motif includes three zinc-binding domains| namely a RING| a B-box type 1 and a B-box type 2| and a coiled-coil region

Colocalized with SLC3A2/4F2hc at the basolateral membrane of kidney cortex proximal tubules and small intestine epithelia of the villi

are primarily involved in metabolism of steroids at the C17 position and also of other substrates

KR103 Rabbit Polyclonal Antibody, 50ul Organelle Studies Mutations in this gene cause