ZAP-70(Phospho Tyr493) Polyclonal Antibody, 20ul Buffer Solutions identified in the human major

identified in the human major histocompatibility complex class I region

An important paralog of this gene is ACKR3

Overexpression

Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy

hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology

ZAP-70(Phospho Tyr493) Polyclonal Antibody, 20ul Buffer Solutions identified in the human majorThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T cell antigen receptor (TCR) stimulation, functions in the initial step of TCR mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene