GABBR2(Phospho Ser893) Rabbit Polyclonal Antibody, 20ul Serum retinal ganglion cell axons expressing

retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment

Expression of this gene is also associated with several types of cancer

This gene encodes a member of the GXGD family of aspartic proteases| which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions| as well as a member of the signal peptide peptidase-like protease (SPPL) family

The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator

autosomal recessive 16

GABBR2(Phospho Ser893) Rabbit Polyclonal Antibody, 20ul Serum retinal ganglion cell axons expressingThe multi pass membrane protein encoded by this gene belongs to the G protein coupled receptor 3 family and GABA B receptor subfamily. The GABA B receptors inhibit neuronal activity through G protein coupled second messenger systems which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA B receptor subunit 1 neither of which is