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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07024] Pipette Filler The protein encoded by this

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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07024] Pipette Filler The protein encoded by thisPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

The protein encoded by this gene is a member of the RAD51 protein family

This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling

This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1

This protein and ATM share similarity with Schizosaccharomyces pombe rad3| a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage

and an RNA recognition motif (RRM) that is not found in RAD52

PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07024] Pipette Filler The protein encoded by thisPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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