CLCN5 Polyclonal Antibody, 20ul Vortex Mixer and overexpressed in colon tumors

and overexpressed in colon tumors

CLCs are involved in membrane potential stabilization

and Biacore surface resonance analysis

The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates

Two transcript variants encoding distinct isoforms have been identified

CLCN5 Polyclonal Antibody, 20ul Vortex Mixer and overexpressed in colon tumorsThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.