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DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02654] Protein Research not all variants give rise

SKU: 38430020910

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DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02654] Protein Research not all variants give riseDNA ligase 4 encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and

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Description

not all variants give rise to a functional enzyme

and is thought to function as a downstream enzyme in the caspase activation cascade

This gene is composed of seven exons

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors

13) involving this gene is associated with X-linked mental retardation

DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02654] Protein Research not all variants give riseDNA ligase 4 encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and

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