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Histone H4 (Tri Methyl Lys21) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Mutations in this gene are

SKU: 38281361431

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Histone H4 (Tri Methyl Lys21) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Mutations in this gene areCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone code and nucleosome remodeling. PTM: Acetylation at

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Description

Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC

GO annotations related to this gene include GTPase activator activity and Rab GTPase binding

The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus

It responds to changes in the cellular environment and represses pol III transcription

Specific anti-human IL-10 antibodies are precoated on a high-affinity ELISA plate

Histone H4 (Tri Methyl Lys21) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Mutations in this gene areCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone code and nucleosome remodeling. PTM: Acetylation at

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