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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03041] Mammalian Expression Defects in this gene are

SKU: 38105385708

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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03041] Mammalian Expression Defects in this gene areERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia

The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube

CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes

Transcriptional repressor of genes that require a bHLH protein for their transcription

and pericentriolar regions of cells

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03041] Mammalian Expression Defects in this gene areERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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