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CD59 Polyclonal Antibody, 50ul[BT-AP01987] Adenovirus Packaging This complex plays a critical

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CD59 Polyclonal Antibody, 50ul[BT-AP01987] Adenovirus Packaging This complex plays a criticalCLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

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Description

This complex plays a critical role in erythrocyte shape and deformability

The protein encoded by this gene belongs to the calreticulin family

Alternatively spliced transcript variants encoding different isoforms have been described for GRM8

It consists of a common heteromeric core enzyme

An important paralog of this gene is REG3G

CD59 Polyclonal Antibody, 50ul[BT-AP01987] Adenovirus Packaging This complex plays a criticalCLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

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