EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator The encoded protein promotes attachment

The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin

The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily

A transcript variant retaining intronic sequence and encoding a shorter isoform has been described

and it plays a role in the increase of cell survival in a caspase-3-dependent pathway

This protein contains one PH domain and one SH3 domain

EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator The encoded protein promotes attachmentThis gene encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.