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Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The gene product is recognized

SKU: 37830212343

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Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The gene product is recognizedThe product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso peptidase, and cleaves ubiquitin from branched poly ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.

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Description

The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies

NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL

Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior

S rRNAs and may also play a role in the biosynthesis of the 60S ribosomal unit

This intronless gene encodes a member of the Kruppel-like family of transcription factors

Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The gene product is recognizedThe product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso peptidase, and cleaves ubiquitin from branched poly ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.

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