FoxO4(Phospho Ser262) Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in this gene have

Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome

Defects in this gene are a cause of Peters-plus syndrome (PPS)

The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER

Alternatively spliced variants which encode different protein isoforms have been described| but only one has been fully characterized

Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma

FoxO4(Phospho Ser262) Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in this gene haveThis gene encodes a member of the O class of winged helix forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants