IDUA Polyclonal Antibody, 20ul Biochemical Reagents This endoplasmic reticulum membrane protein

This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha

78 kDa glucose-regulated protein encoded by HSPA5 is a member of the heat shock protein 70 (HSP70) family

Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death

and five C2H2-type zinc finger motifs

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IDUA Polyclonal Antibody, 20ul Biochemical Reagents This endoplasmic reticulum membrane proteinThis gene encodes an enzyme that hydrolyzes the terminal alpha L iduronic acid residues of two glycosaminoglycans dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).