Cdc25A(Phospho Thr507) Polyclonal Antibody, 50ul Centrifugal Filter Mutations in this gene have

Mutations in this gene have been associated with colorectal and gastric carcinomas

proliferation and network formation by endothelial cells as well as angiogenesis

and inhibition of proliferation of tumor cells

Two transcript variants that encode different isoforms have been found for this gene

The gap junction protein alpha 5 is a component of gap junctions

Cdc25A(Phospho Thr507) Polyclonal Antibody, 50ul Centrifugal Filter Mutations in this gene haveCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.