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IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Alternatively spliced transcript variants encoding

SKU: 37503040901

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IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Alternatively spliced transcript variants encodingThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

Alternatively spliced transcript variants encoding different isoforms have been found for RPL11

interaction is required for cytokinesis but not for viral budding

This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity

Plays a role in transcriptional activation of Wnt-responsive genes

hepatoblastomas

IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Alternatively spliced transcript variants encodingThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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