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ASCL1 Polyclonal Antibody, 100ul[BT-AP00664] RNA Synthesis This gene has been implicated

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ASCL1 Polyclonal Antibody, 100ul[BT-AP00664] RNA Synthesis This gene has been implicatedASCL1 encodes a member of the basic helix loop helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5' CANNTG 3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central

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Description

This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene

and p110-gamma)

The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle

Treslin is involved in the initiation of DNA replication (Kumagai et al

ASCL1 Polyclonal Antibody, 100ul[BT-AP00664] RNA Synthesis This gene has been implicatedASCL1 encodes a member of the basic helix loop helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5' CANNTG 3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central

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