DSC2 Polyclonal Antibody, 20ul Vessels Antibodies to the encoded protein

Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome

The protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial-specific type I membrane receptor that binds thrombin

has both trans-activating and DNA binding activities

Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade

Two alternatively spliced transcripts variants that encode the same protein have been found for this gene

DSC2 Polyclonal Antibody, 20ul Vessels Antibodies to the encoded proteinThis gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are