Presenilin 2 Rabbit Polyclonal Antibody, 100ul Cell Culture Dishes CCT8 encodes the theta subunit

CCT8 encodes the theta subunit of the CCT chaperonin

OCRL encodes an inositol polyphosphate 5-phosphatase

14Z-icosatetraenoic acid binding

The protein encoded by this gene shares similarity with several thiamine pyrophosphate-binding proteins identified in bacteria| yeast| and plants

|Contains 2 cystatin domains

Presenilin 2 Rabbit Polyclonal Antibody, 100ul Cell Culture Dishes CCT8 encodes the theta subunitAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase an enzyme that cleaves APP. Also