IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis Mutations in this gene have

Mutations in this gene have been reported to be associated with nonsyndromic hearing loss

tissue specificity:Overexpressed in psoriasis

The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle

This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations

This protein forms a very tight complex with alpha neurexins

IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis Mutations in this gene haveIKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.