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SEPT9 Polyclonal Antibody, 100ul Oligo Pool The gene product is predicted

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SEPT9 Polyclonal Antibody, 100ul Oligo Pool The gene product is predictedThis gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript

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Description

The gene product is predicted to be a six-transmembrane protein

Tumor necrosis factor ligand superfamily member 10 encoded by TNFSF10 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family

Besides the central nervous system| it is expressed at high levels in peripheral blood leukocytes| and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions

Nuclear export mediator factor facilitates the recognition and ubiquitination of stalled 60S subunits by the ubiquitin ligase listerin

Mutations in PNPT1 have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70

SEPT9 Polyclonal Antibody, 100ul Oligo Pool The gene product is predictedThis gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript

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