FoxO1(Phospho Ser256) Polyclonal Antibody, 20ul Sealing Film A mutation in the mouse

A mutation in the mouse ortholog of this gene results in homeotic| posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants

Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect

Forms heterodimers with TCF3

suggesting its importance in the normal function of this gene

a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development

FoxO1(Phospho Ser256) Polyclonal Antibody, 20ul Sealing Film A mutation in the mouseThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.