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PLZF Monoclonal Antibody, 50ul Measuring Instruments High mobility group box 1

SKU: 36845680001

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PLZF Monoclonal Antibody, 50ul Measuring Instruments High mobility group box 1This gene is a member of the Krueppel C2H2 type zinc finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL).

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Description

High mobility group box 1 plays a role in several cellular processes

CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit) is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily

forms the CDK-activating kinase (CAK) enzymatic complex

CEP41 (centrosomal protein 41) encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain

THOC5 localizes in the nucleus and acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription

PLZF Monoclonal Antibody, 50ul Measuring Instruments High mobility group box 1This gene is a member of the Krueppel C2H2 type zinc finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL).

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