LOXL3 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction Mutations in ABHD12 are associated

Mutations in ABHD12 are associated with the neurodegenerative disease

Among its related pathways are LKB1 signaling events

expression is highest in hippocampus

The encoded protein may also play a role in malarial infection and has been associated with cancer

4-dienoyl-CoA to yield trans-3-enoyl-CoA

LOXL3 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction Mutations in ABHD12 are associatedThis gene encodes a lysyl oxidase which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate spine deformity and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome.