RHG28 Polyclonal Antibody, 20ul Thermo Mix Fusion of ATF1 and FUS

Fusion of ATF1 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I)

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DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al

This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane

RHG28 Polyclonal Antibody, 20ul Thermo Mix Fusion of ATF1 and FUSThe sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,GTPase activator for the Rho type GTPases by converting them to an inactive GDP bound state.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Contains 1 Rho GAP domain.,tissue specificity: Expressed in testis. Expressed at moderate level in kidney and ovary, and weakly expressed in spleen and skeletal muscle.,