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IRF-3 Polyclonal Antibody, 50ul[BT-AP04627] Antibody Development Defects in this gene are

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IRF-3 Polyclonal Antibody, 50ul[BT-AP04627] Antibody Development Defects in this gene areIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed

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Description

Defects in this gene are a cause of several syndromes

other evidence demonstrates that KSR1 regulates Raf in a kinase-independent manner

Probably involved in anxiety and depression

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes

and the development of obesity

IRF-3 Polyclonal Antibody, 50ul[BT-AP04627] Antibody Development Defects in this gene areIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed

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