IL-1Beta Polyclonal Antibody, 50ul[BT-AP04469] Custom DNA Oligos Two alternative transcripts encoding different

Two alternative transcripts encoding different isoforms have been identified

Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA| heparin and the cell surface

mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis

Histone deacetylation modulates chromatin structure

This gene has been found fused to a variety of translocation partner genes in various leukemias

IL-1Beta Polyclonal Antibody, 50ul[BT-AP04469] Custom DNA Oligos Two alternative transcripts encoding differentInterleukin 1 beta encoded by IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1 ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase 2