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LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences LIN54 is a component of

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LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences LIN54 is a component ofSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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Description

LIN54 is a component of the LIN| or DREAM| complex| an essential regulator of cell cycle genes (Schmit et al

This protein may also function in the DNA damage response

and a key role in cardiovascular homeostasis

|PTM:Constitutively sumoylated by SUMO1| SUMO2 and SUMO3

7-transmembrane receptor (GPCR) superfamily

LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences LIN54 is a component ofSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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