TH Polyclonal Antibody, 50ul[BT-AP08990] Cellular Cultivation & Health Management The encoded protein binds numerous

The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors| inositol 1|4|5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling| T-cell activation and trafficking of amyloid beta peptides

The copy number of this gene varies among individuals

and in maintaining extracellular glutamate concentrations below neurotoxic levels

functionally active form and also in an inactive form complexed with C4b-binding protein

and by CTNNB1 and TCF family members in Wnt signaling

TH Polyclonal Antibody, 50ul[BT-AP08990] Cellular Cultivation & Health Management The encoded protein binds numerousTyrosine 3 monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.