JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates The product of this gene

The product of this gene has the lowest sensitivity for these antagonists

The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain

but the full-length nature of these variants has not been determined

Involved in accumulation of zinc in synaptic vesicles

disease:Expressed in a variety of skin disorders| including allergic contact dermatitis| lichen planus and mycosis fungoides

JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates The product of this geneThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).