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E2A Monoclonal Antibody, 50ul Miscellaneous Polymorphisms in this gene may

SKU: 35563678371

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E2A Monoclonal Antibody, 50ul Miscellaneous Polymorphisms in this gene mayThis gene encodes a member of the E protein (class I) family of helix loop helix transcription factors. E proteins activate transcription by binding to regulatory E box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA binding (class IV) helix loop helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development.

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Description

Polymorphisms in this gene may be associated with osteoarthritis in human patients

The encoded protein (ADAM metallopeptidase domain 32) undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease

RCF: 2200×g

Mutations in CEP135 are associated with autosomal recessive primary microcephaly-8

an inhibitor of TNF-alpha functions

E2A Monoclonal Antibody, 50ul Miscellaneous Polymorphisms in this gene mayThis gene encodes a member of the E protein (class I) family of helix loop helix transcription factors. E proteins activate transcription by binding to regulatory E box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA binding (class IV) helix loop helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development.

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