DARPP-32(Phospho Thr75) Polyclonal Antibody, 50ul Cell fragmentation and collection Mutations in VIM causes a

Mutations in VIM causes a dominant

The encoded protein forms a homodimer

This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons

Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin

The encoded protein may play roles in blood vessel maturation and hematopoeisis

DARPP-32(Phospho Thr75) Polyclonal Antibody, 50ul Cell fragmentation and collection Mutations in VIM causes aThis gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.