GPTC8 Polyclonal Antibody, 50ul Molecular Biology Dok-5 and Dok-6 are more

Dok-5 and Dok-6 are more similar to each other than to the other Dok family members

suggesting either heavy glycosylation or dimerization

One isoform lacks the intermembrane region and is secreted outside the cell

The protein encoded by this gene is a lymphocyte-expressed ADAM protein

and is involved in muscular excitation and contraction

GPTC8 Polyclonal Antibody, 50ul Molecular Biology Dok-5 and Dok-6 are moreThe protein encoded by this gene contains an RNA processing domain, a zinc finger domain, a lysine rich region and a serine rich region. A mutation in the serine rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms.