VPS4B Polyclonal Antibody, 50ul Lentiviral Packaging UBE2G1 (ubiquitin conjugating enzyme E2

UBE2G1 (ubiquitin conjugating enzyme E2 G1) encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins

Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection

familial hypercholesterolemia

also found in skin

A pseudogene of this gene is found on chromosome 19

VPS4B Polyclonal Antibody, 50ul Lentiviral Packaging UBE2G1 (ubiquitin conjugating enzyme E2The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog.