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ODC Polyclonal Antibody, 20ul Cell Function Analysis Mutations in this gene are

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ODC Polyclonal Antibody, 20ul Cell Function Analysis Mutations in this gene areSLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5 C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2 oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2 oxoadipate is converted into acetyl CoA.

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Description

Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC)

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are membrane-bound proteins with long N termini containing multiple domains

ODC Polyclonal Antibody, 20ul Cell Function Analysis Mutations in this gene areSLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5 C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2 oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2 oxoadipate is converted into acetyl CoA.

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