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IGF-IIR(Phospho Ser2409) Polyclonal Antibody, 100ul DNA Oligo Synthesis The encoded protein inhibits ectopic

SKU: 34949746770

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IGF-IIR(Phospho Ser2409) Polyclonal Antibody, 100ul DNA Oligo Synthesis The encoded protein inhibits ectopicThis gene encodes a receptor for both insulin like growth factor 2 and mannose 6 phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions including in the intracellular trafficking of lysosomal enzymes the activation of transforming growth factor beta and the degradation of insulin like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with

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Description

The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration

Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles

Can form a heterodimer with ESR2

The protein localizes to membrane protrusions and is often expressed on adult stem cells

hypofibrinogenemia

IGF-IIR(Phospho Ser2409) Polyclonal Antibody, 100ul DNA Oligo Synthesis The encoded protein inhibits ectopicThis gene encodes a receptor for both insulin like growth factor 2 and mannose 6 phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions including in the intracellular trafficking of lysosomal enzymes the activation of transforming growth factor beta and the degradation of insulin like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with

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