p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging Alternative splicing generates additional isoforms

Alternative splicing generates additional isoforms of each of the five growth hormones

is due to mutations in the ALMS1 gene

thereby releasing the attached protein from the plasma membrane

The protein encoded by this gene is 75% identical to the mouse homolog

Widely expressed in fetal tissues

p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging Alternative splicing generates additional isoformsTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.