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HEN1/2 Polyclonal Antibody, 50ul Molecular Biology VRK3 (vaccinia related kinase 3)

SKU: 34507535154

4.1
PLN162.00 PLN201.00

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HEN1/2 Polyclonal Antibody, 50ul Molecular Biology VRK3 (vaccinia related kinase 3)The helix loop helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCL.

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Description

VRK3 (vaccinia related kinase 3) encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases

Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site

Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers

subunit:Interacts with EFNB1

Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration

HEN1/2 Polyclonal Antibody, 50ul Molecular Biology VRK3 (vaccinia related kinase 3)The helix loop helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCL.

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