Tuberin Polyclonal Antibody, 50ul[BT-AP09286] Protein Research Mutations at this locus have

Mutations at this locus have been linked to autosomal recessive deafness

May be required for chromosome segregation during cell division

ADIPOR1 (MIM 607945) and ADIPOR2

The lysophosphatidic acid receptor 1 encoded by LPAR1 is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors

and it is required for the association of centromere-associated protein E with the kinetochore

Tuberin Polyclonal Antibody, 50ul[BT-AP09286] Protein Research Mutations at this locus haveMutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.