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Histone H3 Polyclonal Antibody, 100ul[BT-AP04080] Cell Culture & Maintenance Members of this family are

SKU: 34048969260

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PLN141.00 PLN174.00

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Histone H3 Polyclonal Antibody, 100ul[BT-AP04080] Cell Culture & Maintenance Members of this family areHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin

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Description

Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains

This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes

Epigenetic silencing of this gene has been observed in gliomas

In the mouse

C-Jun-amino-terminal kinase-interacting protein 1 has been shown to prevent MAPK8 mediated activation of transcription factors

Histone H3 Polyclonal Antibody, 100ul[BT-AP04080] Cell Culture & Maintenance Members of this family areHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin

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